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A novel designer drug, 25N-NBOMe, exhibits abuse potential via the dopaminergic system in rodents.
Brain Res Bull. 2019 Jul 4;152:19-26. doi: 10.1016/j.brainresbull.2019.07.002., 2019
Ma SX, Kim HC, Lee SY, Jang CG. TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens. Neurochem Int. 2018 Dec;121:1-7. doi: 10.1016/j.neuint.2018.10.009. Epub 2018 Oct 4., 2018
Ko YH, Kwon SH, Ma SX, Seo JY, Lee BR, Kim K, Kim SY, Lee SY, Jang CG. The memory-enhancing effects of 7,8,4'-trihydroxyisoflavone, a major metabolite of daidzein, are associated with activation of the cholinergic system and BDNF signaling pathway in mice. Brain Res Bull. 2018 Sep;142:197-206. doi: 10.1016/j.brainresbull.2018.07.012. Epub 2018 Jul 19., 2018
Ko YH, Shim KY, Lee SY, Jang CG. Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice. Biomol Ther (Seoul). 2018 Sep 1;26(5):432-438. doi: 10.4062/biomolther.2017.146., 2018
Lee KW, Kim K, Kim HC, Lee SY, Jang CG. The role of striatal Gαq/11 protein in methamphetamine-induced behavioral sensitization in mice. Behav Brain Res. 2018 Jul 2;346:66-72. doi: 10.1016/j.bbr.2017.12.003. Epub 2017 Dec 6., 2018
Seo JY, Ko YH, Ma SX, Lee BR, Lee SY, Jang CG. Repeated restraint stress reduces the acquisition and relapse of methamphetamine-conditioned place preference but not behavioral sensitization. Brain Res Bull. 2018 May;139:99-104. doi: 10.1016/j.brainresbull.2018.01.018. Epub 2018 Feb 5., 2018
Ko YH, Kim SY, Lee SY, Jang CG. 6,7,4'-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice. Eur J Pharmacol. 2018 May 5;826:140-147. doi: 10.1016/j.ejphar.2018.02.048. Epub 2018 Mar 3., 2018
Ko YH, Kwon SH, Hwang JY, Kim KI, Seo JY, Nguyen TL, Lee SY, Kim HC, Jang CG. The Memory-Enhancing Effects of Liquiritigenin by Activation of NMDA Receptors and the CREB Signaling Pathway in Mice. Biomol Ther (Seoul). 2018 Mar 1;26(2):109-114. doi: 10.4062/biomolther.2016.284., 2018
Oh JH, Hwang JY, Hong SI, Ma SX, Seo JY, Lee SY, Kim HC, Jang CG. The new designer drug buphedrone produces rewarding properties via dopamine D1 receptor activation. Addict Biol. 2018 Jan;23(1):69-79. doi: 10.1111/adb.12472. Epub 2016 Oct 27., 2018
Tian YH, Ma SX, Lee KW, Wee S, Koob GF, Lee SY, Jang CG. Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects. Sci Rep. 2018 Jan 17;8(1):882. doi: 10.1038/s41598-018-19207-2., 2018
Ma SX, Kwon SH, Seo JY, Hwang JY, Hong SI, Kim HC, Lee SY, Jang CG. Impairment of opiate-mediated behaviors by the selective TRPV1 antagonist SB366791. Addict Biol. 2017 Nov;22(6):1817-1828. doi: 10.1111/adb.12460. Epub 2016 Oct 11., 2017
Ko YH, Kwon SH, Lee SY, Jang CG. Liquiritigenin ameliorates memory and cognitive impairment through cholinergic and BDNF pathways in the mouse hippocampus. Arch Pharm Res. 2017 Oct;40(10):1209-1217. doi: 10.1007/s12272-017-0954-6. Epub 2017 Sep 22., 2017
Hong SI, Nguyen TL, Ma SX, Kim HC, Lee SY, Jang CG. TRPV1 modulates morphine-induced conditioned place preference via p38 MAPK in the nucleus accumbens. Behav Brain Res. 2017 Sep 15;334:26-33. doi: 10.1016/j.bbr.2017.07.017. Epub 2017 Jul 19., 2017
Hwang JY, Kim JS, Oh JH, Hong SI, Ma SX, Jung YH, Ko YH, Lee SY, Kim HC, Jang CG. The new stimulant designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity. Addict Biol. 2017 Jan;22(1):117-128. doi: 10.1111/adb.12299. Epub 2015 Aug 19., 2017
Kwon SH, Ma SX, Ko YH, Seo JY, Lee BR, Lee TH, Kim SY, Lee SY, Jang CG. Vaccinium bracteatum Thunb. Exerts Anti-Inflammatory Activity by Inhibiting NF-κB Activation in BV-2 Microglial Cells. Biomol Ther (Seoul). 2016 Sep 1;24(5):543-51. doi: 10.4062/biomolther.2015.205., 2016
Hong SI, Kim MJ, You IJ, Kwon SH, Ma SX, Hwang JY, Seo JY, Ko YH, Lee BR, Lee SY, Jang CG. Phentermine induces conditioned rewarding effects via activation of the PI3K/Akt signaling pathway in the nucleus accumbens. Psychopharmacology (Berl). 2016 Apr;233(8):1405-13. doi: 10.1007/s00213-016-4231-z. Epub 2016 Feb 18., 2016
Sa-Ik Hong, Seung-Hwan Kwon, Ji-Young Hwang, Shi-Xun Ma, Jee-Yeon Seo, Yong-Hyun Ko, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jang. Quinpirole increases Melatonin-Augmented Pentobarbital Sleep via cortical ERK, p38 MAPK, and PKC in mice. Biomol Ther (Seoul). 2016 Mar 1;24(2):115-22. doi: 10.4062/biomolther.2015.097., 2016
Kwon SH, Ma SX, Hong SI, Lee SY, Jang CG. Lonicera japonica THUNB. Extract Inhibits Lipopolysaccharide-Stimulated Inflammatory Responses by Suppressing NF-κB Signaling in BV-2 Microglial Cells. J Med Food. 2015 Apr 21. 2015 Jul;18(7):762-75. doi: 10.1089/jmf.2014.3341. Epub 2015 Apr 21., 2015
Kwon SH, Hong SI, Ma SX, Lee SY, Jang CG. 3',4',7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress. Food Chem Toxicol. 2015 Jun;80:41-51. doi:10.1016/j.fct.2015.02.014. Epub 2015 Feb 23., 2015
Jung YH, Hong SI, Ma SX, Hwang JY, Kim JS, Lee JH, Seo JY, Lee SY, Jang CG. Strain differences in the chronic mild stress animal model of depression and anxiety in mice. Biomol Ther (Seoul). 2014 Sep;22(5):453-9. doi: 0.4062/biomolther.2014.058. Epub 2014 Sep 30., 2014
Kwon SH, Ma SX, Lee SY, Jang CG. Sulfuretin inhibits 6-hydroxydopamine-induced neuronal cell death via reactive oxygen species-dependent mechanisms in human neuroblastoma SH-SY5Y cells. Neurochem Int. 2014 Jul;74:53-64. doi: 10.1016/j.neuint.2014.04.016. Epub 2014 May 4., 2014
Nguyen TL, Kwon SH, Hong SI, Ma SX, Jung YH, Hwang JY, Kim HC, Lee SY, Jang CG. Transient receptor potential vanilloid type 1 channel may modulate opioid reward. Neuropsychopharmacology. 2014 Sep;39(10):2414-22. doi: 10.1038/npp.2014.90. Epub 2014 Apr 15., 2014
Kwon SH, Ma SX, Hong SI, Kim SY, Lee SY, Jang CG. Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells. J Ethnopharmacol. 2014 Feb 27;152(1):173-82. doi: 10.1016/j.jep.2013.12.048. Epub 2014 Jan 15., 2014
Jang CG, Whitfield T, Schulteis G, Koob GF, Wee S. A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats. Psychopharmacology (Berl). 2013 Feb;225(3):753-63. doi: 10.1007/s00213-012-2864-0. Epub 2012 Sep 25., 2013
Kwon SH, Ma SX, Joo HJ, Lee SY, Jang CG. Inhibitory Effects of Eucommia ulmoides Oliv. Bark on Scopolamine-Induced Learning and Memory Deficits in Mice. Biomol Ther (Seoul). 2013 Nov;21(6):462-9. doi: 10.4062/biomolther.2013.074., 2013
Lee SY, You IJ, Kim MJ, Kwon SH, Hong SI, Kim JH, Jang MH, Oh SM, Chung KH, Lee SY, Jang CG. The abuse potential of oxethazaine: effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models. Pharmacol Biochem Behav. 2013 Apr;105:98-104. doi: 10.1016/j.pbb.2013.01.022. Epub 2013 Feb 8., 2013
Jung YH, Ha RR, Kwon SH, Hong SI, Lee KH, Kim SY, Lee SY, Jang CG. Anxiolytic effects of Julibroside C1 isolated from Albizzia julibrissin in mice.Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 1;44:184-92. doi: 10.1016/j.pnpbp.2013.02.012. Epub 2013 Feb 26., 2013
You IJ, Jung YH, Kim MJ, Kwon SH, Hong SI, Lee SY, Jang CG. Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT₁A, GABA(A), and NMDA receptors. Neuropharmacology 2012 Feb.;62(2):1034-1043., 2012
Choi CI, Bae JW, Jang CG, Lee SY. Tamsulosin Exposure Is Significantly Increased by the CYP2D6*10/*10 Genotype. J Clin Pharmacol 2012 Jan., 2012
Choi CI, Kim MJ, Chung EK, Lee HI, Jang CG, Bae JW, Lee SY. CYP2C9 3 and 13 alleles significantly affect the pharmacokinetics of irbesartan in healthy Korean subjects. Eur J Clin Pharmacol 2012 Feb.;68(2):149-154., 2012
Choi CI, Bae JW, Lee HI, Jang CG, Sohn UD, Lee SY. Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2012 Feb.;885-886:103-108., 2012
Kwon SH, Hong SI, Jung YH, Kim MJ, Kim SY, Kim HC, Lee SY, Jang CG. Lonicera japonica THUNB. protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of MAPKs, PI3K/Akt, and NF-κB in SH-SY5Y cells. Food Chem. Toxicol. 2012 Mar.;50(3-4):797-807., 2012
Hwang SH, Shin EJ, Shin TJ, Lee BH, Choi SH, Kang J, Kim HJ, Kwon SH, Jang CG, Lee JH, Kim HC, Nah SY. Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Attenuates Alzheimer's Disease-Related Neuropathies: Involvement of Non-Amyloidogenic Processing. J Alzheimers Dis 2012 Apr., 2012
Choi CI, Lee YJ, Lee HI, Kim BH, Kim MJ, Jang CG, Bae JW, Lee SY. Effects of the SLCO1B1*15 allele on the pharmacokinetics of pitavastatin. Xenobiotica 2012 May;42(5):496-501., 2012
Lee S, Kim J, In S, Choi H, Oh SM, Jang CG, Chung KH. Development of a simultaneous analytical method for selected anorectics, methamphetamine, MDMA, and their metabolites in hair using LC-MS/MS to prove anorectics abuse. Anal Bioanal Chem 2012 May;403(5):1385-1394., 2012
Bae JW, Choi CI, Lee JH, Jang CG, Chung MW, Lee SY. Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. Eur J Clin Pharmacol. 2011 Jan;67(1):39-45., 2011
Kwon SH, Lee HK, Kim JA, Hong SI, Kim SY, Jo TH, Park YI, Lee CK, Kim YB, Lee SY, Jang CG. Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in mice. Neurosci Lett. 2011 Jan 3;487(1):123-7., 2011
Nguyen TL, Tian YH, You IJ, Lee SY, Jang CG. Modafinil-induced conditioned place preference via dopaminergic system in mice. Synapse. 2011 Aug;65(8):733-41., 2011
Bae J-W, Jang C-G, Lee S-Y. Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites. J Clin Pharmacol 2011 Dec.;51(12):1704-1711., 2011
Kwon SH, Hong SI, Kim JA, Jung YH, Kim SY, Kim HC, Lee SY, Jang CG. The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells. Food Chem Toxicol. 2011 Apr;49(4):1011-9., 2011
Kwon SH, Kim JA, Hong SI, Jung YH, Kim HC, Lee SY, Jang CG. Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells. Neurochem Int. 2011 Mar;58(4):533-41., 2011
Lee KW, Kim HC, Lee SY, Jang CG. Methamphetamine-sensitized mice are accompanied by memory impairment and reduction of N-methyl-d-aspartate receptor ligand binding in the prefrontal cortex and hippocampus. Neuroscience. 2011 Mar 31;178:101-7., 2011
Bae JW, Choi CI, Jang CG, Lee SY. Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomed Chromatogr. 2011 Feb 4., 2011
Bae JW, Choi CI, Jang CG, Lee SY. Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam. Br J Clin Pharmacol. 2011 Apr;71(4):550-5., 2011
Tian YH, Hwan Kim S, Lee SY, Jang CG. Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring. Synapse. 2011 Oct;65(10):1032-41., 2011
Choi CI, Kim MJ, Jang CG, Park YS, Bae JW, Lee SY. Effects of the CYP2C9*1/*13 Genotype on the Pharmacokinetics of Lornoxicam. Basic Clin Pharmacol Toxicol. 2011 Jul 5., 2011
Bae JW, Choi CI, Kim MJ, Oh DH, Keum SK, Park JI, Kim BH, Bang HK, Oh SG, Kang BS, Park HJ, Kim HD, Ha JH, Shin HJ, Kim YH, Na HS, Chung MW, Jang CG, Lee SY. Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics. Acta Pharmacol Sin. 2011 Aug 15., 2011
Choi CI, Kim MJ, Chung EK, Lee HI, Jang CG, Bae JW, Lee SY. CYP2C9*3 and *13 alleles significantly affect the pharmacokinetics of irbesartan in healthy Korean subjects. Eur J Clin Pharmacol. 2011 Aug 13., 2011
Shin EJ, Bach JH, Nguyen TT, Jung BD, Oh KW, Kim MJ, Jang CG, Ali SF, Ko SK, Yang CH, Kim HC. Gastrodia Elata Bl Attenuates Cocaine-Induced Conditioned Place Preference and Convulsion, but not Behavioral Sensitization in Mice: Importance of GABA(A) Receptors. Curr Neuropharmacol. 2011 Mar;9(1):26-9., 2011
Shin EJ, Bach JH, Nguyen TT, Nguyen XK, Jung BD, Oh KW, Kim MJ, Ko SK, Jang CG, Ali SF, Kim HC. Gastrodia elata bl attenuates methamphetamine-induced dopaminergic toxicity via inhibiting oxidative burdens. Curr Neuropharmacol. 2011 Mar;9(1):118-21., 2011
Bae JW, Jang CG, Lee SY. Effects of Clopidogrel on the Pharmacokinetics of Sibutramine and Its Active Metabolites. The Journal of Clinical Pharmacology 2011 Dec.;51(12):1704-1711., 2011
Yoo JH, Lee HK, Kim HC, Lee SY, Jang CG. GABA(A) receptors mediate the attenuating effects of a 5-HT(3) receptor antagonist on methamphetamine-induced behavioral sensitization in mice. Synapse. 2010 Apr;64(4):274-9., 2010
Nguyen TL, You IJ, Oh S, Yang CH, Lee SY, Jang CG. Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice. Neurosci Lett. 2010 Feb 26;471(1):38-42., 2010
Tian YH, Lee SY, Kim HC, Jang CG. Repeated methamphetamine treatment increases expression of TRPV1 mRNA in the frontal cortex but not in the striatum or hippocampus of mice. Neurosci Lett. 2010 Mar 12;472(1):61-4., 2010
Bae JW, Kim MJ, Jang CG, Lee SY. Protective effects of heme oxygenase-1 against MPP(+)-induced cytotoxicity in PC-12 cells. Neurol Sci. 2010 Jun;31(3):307-13., 2010
Tian YH, Baek JH, Lee SY, Jang CG. Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice. Synapse. 2010 Jun;64(6):432-9., 2010
Nguyen TL, Nam YS, Lee SY, Kim HC, Jang CG. Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice. Br J Anaesth. 2010 Nov;105(5):668-74., 2010
Kwon SH, Lee HK, Kim JA, Hong SI, Kim HC, Jo TH, Park YI, Lee CK, Kim YB, Lee SY, Jang CG. Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice. Eur J Pharmacol. 2010 Dec 15;649(1-3):210-7., 2010
Bae JW, Kim JH, Choi CI, Kim MJ, Kim HJ, Byun SA, Chang YS, Jang CG, Park YS, Lee SY. Effect of CYP2C9*3 allele on the pharmacokinetics of naproxen in Korean subjects. Arch Pharm Res. 2009 Feb;32(2):269-73., 2009
Jin CH, Shin EJ, Park JB, Jang CG, Li Z, Kim MS, Koo KH, Yoon HJ, Park SJ, Choi WC, Yamada K, Nabeshima T, Kim HC. Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment. J Neurosci Res. 2009 Dec;87(16):3658-70., 2009
Shin EJ, Jang CG, Bing G, Park DH, Oh CH, Koo KH, Oh KW, Yamada K, Nabeshima T, Kim HC. Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice. Drug Alcohol Depend. 2009 Sep 1;104(1-2):175-84., 2009
Kwon SH, Kim HC, Lee SY, Jang CG. Loganin improves learning and memory impairments induced by scopolamine in mice. Eur J Pharmacol. 2009 Oct 1;619(1-3):44-9., 2009
Moon E, Her Y, Lee JB, Park JH, Lee EH, Kim SH, Oh MS, Jang CG, Kim SY. The multi-herbal medicine Gongjin-dan enhances memory and learning tasks via NGF regulation. Neurosci Lett. 2009 Dec 11;466(3):114-9., 2009
Yoo JH, Nam YS, Lee SY, Jang CG. Dopamine neurotransmission is involved in the attenuating effects of 5-HT3 receptor antagonist MDL 72222 on acute methamphetamine-induced locomotor hyperactivity in mice. Synapse. 2008 Jan;62(1):8-13., 2008
Yang MH, Kim S, Jung MS, Shim JH, Ryu NK, Yook YJ, Jang CG, Bahk YY, Kim KW, Park JH. Proteomic analysis of methamphetamine-induced reinforcement processes within the mesolimbic dopamine system. Addict Biol. 2008 Sep;13(3-4):287-94., 2008
Lee KW, Tian YH, You IJ, Kwon SH, Ha RR, Lee SY, Kim HC, Jang CG. Blockade of M1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect. Neuroscience. 2008 Jun 2;153(4):1235-44., 2008
Tian YH, Lee KW, You IJ, Lee SY, Jang CG. 7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat. Synapse. 2008 Aug;62(8):582-9., 2008
Lee BH, Lee JH, Lee SM, Jeong SM, Yoon IS, Lee JH, Choi SH, Pyo MK, Rhim H, Kim HC, Jang CG, Lee BC, Park CS, Nah SY. Identification of ginsenoside interaction sites in 5-HT3A receptors. Neuropharmacology. 2007 Mar;52(4):1139-50., 2007
Bae JW, Kim MJ, Park YS, Myung CS, Jang CG, Lee SY. Considerable interindividual variation in the pharmacokinetics of tolperisone HCl. Int J Clin Pharmacol Ther. 2007 Feb;45(2):110-3., 2007
Kim JH, Kim SY, Lee SY, Jang CG. Antidepressant-like effects of Albizzia julibrissin in mice: involvement of the 5-HT1A receptor system. Pharmacol Biochem Behav. 2007 May;87(1):41-7., 2007
Yu HS, Lee SY, Jang CG. Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice. Pharmacol Biochem Behav. 2007 May;87(1):164-70., 2007
Yoon BH, Jung JW, Lee JJ, Cho YW, Jang CG, Jin C, Oh TH, Ryu JH. Anxiolytic-like effects of sinapic acid in mice. Life Sci. 2007 Jun 27;81(3):234-40., 2007
Bae JW, Kim MJ, Jang CG, Lee SY. Determination of meloxicam in human plasma using a HPLC method with UV detection and its application to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Nov 1;859(1):69-73., 2007
Shin EJ, Jeong JH, Kim HJ, Jang CG, Yamada K, Nabeshima T, Kim HC. Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D1-like receptors in mice. J Pharmacol Sci. 2007 Dec;105(4):367-71., 2007
Bae JW, Park YS, Sohn UD, Myung CS, Ryu BK, Jang CG, Lee SY. HPLC determination of tolperisone in human plasma. Arch Pharm Res. 2006 Apr;29(4):339-42., 2006
Park MJ, Lee SK, Lim MA, Chung HS, Cho SI, Jang CG, Lee SM. Effect of alpha-tocopherol and deferoxamine on methamphetamine-induced neurotoxicity. Brain Res. 2006 Sep 13;1109(1):176-82., 2006
Yoo JH, Yang EM, Cho JH, Lee JH, Jeong SM, Nah SY, Kim HC, Kim KW, Kim SH, Lee SY, Jang CG. Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice. Neuroscience. 2006 Nov 3;142(4):953-61., 2006
Yoo JH, Cho JH, Yu HS, Lee KW, Lee BH, Jeong SM, Nah SY, Kim HC, Lee SY, Jang CG. Involvement of 5-HT receptors in the development and expression of methamphetamine-induced behavioral sensitization: 5-HT receptor channel and binding study. J Neurochem. 2006 Nov;99(3):976-88., 2006
Yoo JH, Cho JH, Lee SY, Loh HH, Ho IK, Jang CG. Reduced nNOS expression induced by repeated nicotine treatment in mu-opioid receptor knockout mice. Neurosci Lett. 2005 May 20-27;380(1-2):70-4., 2005
Yoo JH, Cho JH, Lee SY, Loh HH, Ho IK, Jang CG. A lack of mu-opioid receptors modulates the expressions of neuropeptide Y and substance P mRNA. Neurosci Lett. 2005 Aug 12-19;384(1-2):29-32., 2005
Jung JW, Cho JH, Ahn NY, Oh HR, Kim SY, Jang CG, Ryu JH. Effect of chronic Albizzia julibrissin treatment on 5-hydroxytryptamine1A receptors in rat brain. Pharmacol Biochem Behav. 2005 May;81(1):205-10., 2005
Kang M, Pyun KH, Jang CG, Kim H, Bae H, Shim I. Nelumbinis Semen reverses a decrease in hippocampal 5-HT release induced by chronic mild stress in rats. J Pharm Pharmacol. 2005 May;57(5):651-6., 2005
Lee JH, Jeong SM, Kim JH, Lee BH, Yoon IS, Lee JH, Choi SH, Kim DH, Rhim H, Kim SS, Kim JI, Jang CG, Song JH, Nah SY. Characteristics of ginsenoside Rg3-mediated brain Na+ current inhibition. Mol Pharmacol. 2005 Oct;68(4):1114-26., 2005
Jeong SM, Park HK, Yoon IS, Lee JH, Kim JH, Jang CG, Lee CJ, Nah SY. Cloning and expression of Ca2+-activated chloride channel from rat brain. Biochem Biophys Res Commun. 2005 Aug 26;334(2):569-76., 2005
Bae JW, Kim HK, Kim JH, Yang SI, Kim MJ, Jang CG, Park YS, Lee SY. Allele and genotype frequencies of CYP2C9 in a Korean population. Br J Clin Pharmacol. 2005 Oct;60(4):418-22., 2005
Kim HC, Shin EJ, Jang CG, Lee MK, Eun JS, Hong JT, Oh KW. Pharmacological action of Panax ginseng on the behavioral toxicities induced by psychotropic agents. Arch Pharm Res. 2005 Sep;28(9):995-1001., 2005
Yoo JH, Cho JH, Lee SY, Lee S, Loh HH, Ho IK, Jang CG. Differential effects of morphine- and cocaine-induced nNOS immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors. Neurosci Lett. 2006 Mar 6;395(2):98-102., 2005
Lee SY, Jang CG. Increases in [(3)H]-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor binding and mRNA expression of AMPA-sensitive glutamate receptor A (GluR-A) subunits in rats withdrawn from butorphanol. J Toxicol Environ Health A. 2005 Dec 10;68(23-24):2163-74., 2005
Yoo JH, Lee SY, Loh HH, Ho IK, Jang CG. Loss of nicotine-induced behavioral sensitization in micro-opioid receptor knockout mice. Synapse. 2004 Mar 15;51(4):219-23., 2004
Yang SI, Park HY, Lee SH, Lee SJ, Han OY, Lim SC, Jang CG, Lee WS, Shin YH, Kim JJ, Lee SY. Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone. Pharmacology. 2004 Jul;71(3):150-6., 2004
Kwon YS, Nabeshima T, Shin EJ, Chun W, Jhoo JH, Jhoo WK, Wie MB, Jang CG, Chung H, Sung YE, Kim HC. PAP 9704, a Korean herbal medicine attenuates methamphetamine-induced hyperlocomotion via adenosine A2A receptor stimulation in mice. Biol Pharm Bull. 2004 Jun;27(6):906-9., 2004
Yoo JH, Lee SY, Loh HH, Ho IK, Jang CG. Altered emotional behaviors and the expression of 5-HT1A and M1 muscarinic receptors in micro-opioid receptor knockout mice. Synapse. 2004 Nov;54(2):72-82., 2004
Jang CG, Kang M, Cho JH, Lee SB, Kim H, Park S, Lee J, Park SK, Hong M, Shin MK, Shim IS, Bae H. Nelumbinis Semen reverses a decrease in 5-HT1A receptor binding induced by chronic mild stress, a depression-like symptom. Arch Pharm Res. 2004 Oct;27(10):1065-72., 2004
Park Y, Jang CG, Yang KH, Loh HH, Ma T, Ho IK. Regional specific increases of [3H]AMPA binding and mRNA expression of AMPA receptors in the brain of mu-opioid receptor knockout mice. Brain Res Mol Brain Res. 2003 May 12;113(1-2):116-23., 2003
Yoo JH, Yang EM, Lee SY, Loh HH, Ho IK, Jang CG. Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice. Neurosci Lett. 2003 Jun 19;344(1):37-40., 2003
Lee SH, Jang CG, Lee SY. Tyrosine kinase is involved in hemin-induced pyresis. Arch Pharm Res. 2003 May;26(5):411-5., 2003
SY, Song DK, Jang CG. Effects of Coptis japonica on morphine-induced conditioned place preference in mice. Arch Pharm Res. 2003 Jul;26(7):540-4., 2003
Jang CG, Lee SY, Yoo JH, Yan JJ, Song DK, Loh HH, Ho IK. Impaired water maze learning performance in mu-opioid receptor knockout mice. Brain Res Mol Brain Res. 2003 Sep 10;117(1):68-72., 2003
Jang CG, Lee SJ, Yang SI, Kim JH, Sohn UD, Lee SY. Carbon monoxide as a novel central pyrogenic mediator. Arch Pharm Res. 2002 Jun;25(3):343-8., 2002
Jang CG, Lee SY, Lee HK, Suh HW, Song DK. Time courses of pCREB expression after dopaminergic stimulation by apomorphine in mouse brain. Arch Pharm Res. 2002 Jun;25(3):370-4., 2002
Woo SH, Kim HS, Yun JS, Lee MK, Oh KW, Seong YH, Oh SK, Jang CG. Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity. Pharmacol Res. 2001 Apr;43(4):335-40., 2001
Park Y, Ho IK, Jang CG, Tanaka S, Ma T, Loh HH, Ko KH. Effects of morphine on pentobarbital-induced responses in mu-opioid receptor knockout mice. Brain Res Bull. 2001 Mar 15;54(5):527-31., 2001
Jang CG, Lee SY, Loh HH, Ho IK. Lack of mu-opioid receptor leads to an increase in the NMDA receptor subunit mRNA expression and NMDA-induced convulsion. Brain Res Mol Brain Res. 2001 Oct 19;94(1-2):105-11., 2001
Jang CG, Lee SY, Park Y, Ma T, Loh HH, Ho IK. Differential effects of morphine, DPDPE, and U-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice. Brain Res Mol Brain Res. 2001 Oct 19;94(1-2):197-9., 2001
Yun JS, Kim HS, Lee MK, Oh KW, Jang CG, Park WK, Seong YH, Lee SC, Oh SK. Inhibitory effects of MK-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine. Pharmacol Res. 2001 Dec;44(6):473-9., 2001
Lee HU, Lee HJ, Park HY, Lee SH, Jang CG, Lee SY. Effects of heme oxygenase system on the cyclooxygenase in the primary cultured hypothalamic cells. Arch Pharm Res. 2001 Dec;24(6):607-12., 2001
Jang CG, Lee SY. NMDA-type glutamatergic modulation in dopaminergic activation measured by apomorphine-induced cage climbing behaviors. Arch Pharm Res. 2001 Dec;24(6):613-7., 2001
Lim HK, Kim HS, Choi HS, Oh S, Jang CG, Choi J, Kim SH, Chang MJ. Effects of acetylbergenin against D -galactosamine-induced hepatotoxicity in rats. Pharmacol Res. 2000 Nov;42(5):471-4., 2000
Kim YH, Choi MR, Song DK, Huh SO, Jang CG, Suh HW. Regulation of c-fos gene expression by lipopolysaccharide and cycloheximide in C6 rat glioma cells. Brain Res. 2000 Jul 28;872(1-2):227-30., 2000
Kim HS, Park IS, Lim HK, Choi HS, Oh S, Park WK, Jang CG, Kim SH, Chang MJ. N-Methyl-D-aspartate receptor antagonists enhance the head-twitch response, a 5-hydroxytryptamine2 receptor-mediated behaviour, in reserpine-treated mice. J Pharm Pharmacol. 2000 Jun;52(6):717-22., 2000
Jang CG, Rockhold RW, Ho IK. An autoradiographic study of [3H]AMPA receptor binding and in situ hybridization of AMPA sensitive glutamate receptor A (GluR-A) subunits following morphine withdrawal in the rat brain. Brain Res Bull. 2000 Jun;52(3):217-21., 2000
Park Y, Jang CG, Ho IK, Ko KH. kappa-opioid agonist stimulated regional distribution of [(35)S]GTPgammas binding in butorphanol continuously infused rat. Brain Res Bull. 2000 May 1;52(1):17-20., 1999
Oh S, Jang CG, Ma T, Ho IK. Activation of protein kinase C by phorbol dibutyrate modulates GABAA receptor binding in rat brain slices. Brain Res. 1999 Dec 11;850(1-2):158-65., 1999
Jang CG, Oh S, Zhu H, Ho IK. Autoradiography of [3H]glutamate binding during pentobarbital tolerance and withdrawal in the rat. Brain Res Bull. 1999 Jan 1;48(1):99-102., 1999
Jang CG, Rockhold RW, Ho IK. Withdrawal from butorphanol dependence alters binding of [3H]phorbol dibutyrate to protein kinase C, but not of [3H]forskolin to adenylate cyclase. Brain Res. 1999 Mar 13;821(2):520-5., 1999
Zhu H, Jang CG, Ma T, Oh S, Rockhold RW, Ho IK. Region specific expression of NMDA receptor NR1 subunit mRNA in hypothalamus and pons following chronic morphine treatment. Eur J Pharmacol. 1999 Jan 15;365(1):47-54., 1999
Jang CG, Oh S, Ho IK. Changes in NMDAR2 subunit mRNA levels during pentobarbital tolerance/withdrawal in the rat brain: an in situ hybridization study. Neurochem Res. 1998 Nov;23(11):1371-7., 1998
Kim HS, Hong YT, Jang CG. Effects of the ginsenosides Rg1 and Rb1 on morphine-induced hyperactivity and reinforcement in mice. J Pharm Pharmacol. 1998 May;50(5):555-60., 1998
Oh S, Jang CG, Ho IK. Activation of protein kinase C by phorbol dibutyrate potentiates [3H]MK-801 binding in rat brain slices. Brain Res. 1998 May 18;793(1-2):337-40., 1998
Kim HS, Hong YT, Oh KW, Seong YH, Rheu HM, Cho DH, Oh S, Park WK, Jang CG. Inhibition by ginsenosides Rb1 and Rg1 of methamphetamine-induced hyperactivity, conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice. Gen Pharmacol. 1998 May;30(5):783-9., 1998
Kim HS, Jang CG, Oh KW, Oh S, Rheu HM, Rhee GS, Seong YH, Park WK. Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice. J Ethnopharmacol. 1998 Feb;60(1):33-42., 1998
Kim HS, Park WK, Jang CG, Oh KW, Kong JY, Oh S, Rheu HM, Cho DH, Kang SY. Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice. Behav Brain Res. 1997 Apr;85(1):37-46., 1997
Kim HS, Jang CG. MK-801 inhibits methamphetamine-induced conditioned place preference and behavioral sensitization to apomorphine in mice. Brain Res Bull. 1997;44(3):221-7., 1997
Kim HS, Jang CG, Park WK. Inhibition by MK-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice. Pharmacol Biochem Behav. 1996 Sep;55(1):11-7., 1996
Kim HS, Jang CG, Park WK, Oh KW, Rheu HM, Cho DH, Oh S. Blockade by ginseng total saponin of methamphetamine-induced hyperactivity and conditioned place preference in mice. Gen Pharmacol. 1996 Mar;27(2):199-204., 1996
Kim HS, Park WK, Jang CG, Oh S. Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice. Brain Res Bull. 1996;40(3):201-7., 1996
Kim HS, Rhee GS, Jung JY, Lee JH, Jang CG, Park WK. Inhibition by noncompetitive NMDA receptor antagonists of apomorphine-induced climbing behavior in mice. Life Sci. 1996;58(17):1397-402., 1996
Kim HS, Jang CG, Lee MK. Antinarcotic effects of the standardized ginseng extract G115 on morphine. Planta Med. 1990 Apr;56(2):158-63., 1990
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